Your doctor has beneficial a medicine called Casodex as therapy to your prostate cancer. The most common unintended effects of bicalutamide embrace hot flashes , swelling or ache of the breasts, ache generally, fatigue, infection, nausea, constipation, swelling of the limbs, diarrhea, anemia, increased urinary frequency , particularly at evening, and blood within the urine.
Contraception MalesAntiandrogen therapy might cause morphological modifications in spermatozoa see Nonclinical Toxicology (thirteen.1). Based on findings in animal reproduction studies and its mechanism of action, advise male patients with female companions of reproductive potential to make use of efficient contraception during remedy and for 130 days after the final dose of CASODEX see Use in Particular Populations (eight.1) and Clinical Pharmacology (12.1). InfertilityMalesBased on animal research, CASODEX can lead to inhibition of spermatogenesis and will impair fertility in males of reproductive potential.
In generic medication for casodex with severe liver impairment (n=4), although there was a 76% improve within the half-life (5.9 and 10.four days for regular and impaired patients, respectively) of the active enantiomer of bicalutamide no dosage adjustment is critical see Use in Specific Populations (8.6).
You probably have diabetes or are at risk for growing diabetes, talk about along with your physician how this medication could affect your medical situation, how your medical condition could have an effect on the dosing and effectiveness of this medicine, and whether or not any special monitoring is required.
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ANAHEIM, CA—Preliminary results from the Early Prostate Most cancers (EPC) Trial Program indicate that therapy of localized or regionally advanced prostate most cancers with bicalutamide can scale back the danger of illness progression by forty two %.
tab casodex , Yonese J, Fukagai T, Kamba T, Nishimura Okay, Nozawa M, Mansbach H, Theeuwes A, Beer TM, Tombal B, et al. Enzalutamide in Japanese patients with chemotherapy-naive, metastatic castration-resistant prostate most cancers: a submit-hoc evaluation of the placebo-managed PREVAIL trial.
Within the multi-middle, double-blind, managed clinical trial evaluating CASODEX 50 mg once every day with flutamide 250 mg three times a day, every together with an LHRH analog, the following hostile reactions with an incidence of 5% or better, regardless of causality, have been reported.